Publications

Listed on this page are scientific publications by users of PPS or of the platforms at the respective founding university. Notify PPS of new publications where proteins from PPS have been used.

Publications 2023

1. Ainelo, A., et al. (2023). "The structure of DarB in complex with Rel(NTD) reveals nonribosomal activation of Rel stringent factors." Sci Adv 9(3): eade4077.

2. Bahnan, W., et al. (2023). "A human monoclonal antibody bivalently binding two different epitopes in streptococcal M protein mediates immune function." EMBO Mol Med 15(2): e16208.

3. Banijamali, E., et al. (2023). "RNA:RNA interaction in ternary complexes resolved by chemical probing." RNA 29(3): 317-329.

4. Barcenas-Walls, J. R., et al. (2023). "Nano-CUT&Tag for multimodal chromatin profiling at single-cell resolution." Nat Protoc.

5. Bartosovic, M. and G. Castelo-Branco (2023). "Multimodal chromatin profiling using nanobody-based single-cell CUT&Tag." Nat Biotechnol 41(6): 794-805.

6. Berger, K., et al. (2023). "Interleukin-6 Induces Stem Cell Propagation through Liaison with the Sortilin–Progranulin Axis in Breast Cancer." Cancers 15(24).

7. Besavilla, D. F., et al. (2023). "Pre-existing CD4 T cell help boosts antibody responses but has limited impact on germinal center, antigen-specific B cell frequencies after influenza infection." Frontiers in Immunology 14.

8. Brown, J. I., et al. (2023). "Cycloguanil and Analogues Potently Target DHFR in Cancer Cells to Elicit Anti-Cancer Activity." Metabolites 13(2).

9. Decker, D., et al. (2023). "Exploring Redox Modulation of Plant UDP-Glucose Pyrophosphorylase." Int J Mol Sci 24(10).

10. Doimo, M., et al. (2023). "Enhanced mitochondrial G-quadruplex formation impedes replication fork progression leading to mtDNA loss in human cells." Nucleic Acids Res 51(14): 7392-7408.

11. Eltschkner, S., et al. (2023). "The structure of songbird MHC class I reveals antigen binding that is flexible at the N-terminus and static at the C-terminus." Frontiers in Immunology 14.

12. Falker-Gieske, C., et al. (2023). "Resistance to chicken amyloid arthropathy is associated with a dysfunctional mutation in serum amyloid A." Faseb Journal 37(1).

13. Frick, I. M., et al. (2023). "IdeS, a secreted proteinase of Streptococcus pyogenes, is bound to a nuclease at the bacterial surface where it inactivates opsonizing IgG antibodies." J Biol Chem 299(11): 105345.

14. Gallego, P., et al. (2023). "The intestinal MUC2 mucin C-terminus is stabilized by an extra disulfide bond in comparison to von Willebrand factor and other gel-forming mucins." Nat Commun 14(1): 1969.

15. García-Revilla, J., et al. (2023). "Galectin-3 shapes toxic alpha-synuclein strains in Parkinson’s disease." Acta Neuropathologica 146(1): 51-75.

16. Happonen, L. J. (2023). "Affinity-Purification Combined with Crosslinking Mass Spectrometry for Identification and Structural Modeling of Host-Pathogen Protein-Protein Complexes." Methods Mol Biol 2674: 181-200.

17. He, Y., et al. (2023). "A subset of antibodies targeting citrullinated proteins confers protection from rheumatoid arthritis." Nat Commun 14(1): 691.

18. Huttner, A., et al. (2023). "Antibody responses to recombinant vesicular stomatitis virus-Zaire Ebolavirus vaccination for Ebola virus disease across doses and continents: 5-year durability." Clin Microbiol Infect 29(12): 1587-1594.

19. Jaiman, D., R. Nagampalli and K. Persson (2023). "A comparative analysis of lipoprotein transport proteins: LolA and LolB from Vibrio cholerae and LolA from Porphyromonas gingivalis." Sci Rep 13(1): 6605.

20. Jons, D., et al. (2023). "Seroreactivity against lytic, latent and possible cross-reactive EBV antigens appears on average 10 years before MS induced preclinical neuroaxonal damage." J Neurol Neurosurg Psychiatry.

21. Knecht, W., et al. (2023). "Oligomeric State of β-Coronavirus Non-Structural Protein 10 Stimulators Studied by Small Angle X-ray Scattering." Int J Mol Sci 24(17).

22. Kosek, D. M., et al. (2023). "Efficient 3'-pairing renders microRNA targeting less sensitive to mRNA seed accessibility." Nucleic Acids Res 51(20): 11162-11177.

23. Li, T., et al. (2023). "Pathogenic antibody response to glucose-6-phosphate isomerase targets a modified epitope uniquely exposed on joint cartilage." Ann Rheum Dis 82(6): 799-808.

24. Lidstrom, T., et al. (2023). "Extracellular Galectin 4 Drives Immune Evasion and Promotes T-cell Apoptosis in Pancreatic Cancer." Cancer Immunol Res 11(1): 72-92.

25. Mahanti, M., et al. (2023). "Ligand Sulfur Oxidation State Progressively Alters Galectin-3-Ligand Complex Conformations To Induce Affinity-Influencing Hydrogen Bonds." Journal of Medicinal Chemistry 66(21): 14716-14723.

26. Moller, M., et al. (2023). "An easy-to-use high-throughput selection system for the discovery of recombinant protein binders from alternative scaffold libraries." Protein Eng Des Sel 36.

27. Nair, R. R. and D. I. Andersson (2023). "Interspecies interaction reduces selection for antibiotic resistance in Escherichia coli." Commun Biol 6(1): 331.

28. Palica, K., et al. (2023). "α-Aminophosphonate inhibitors of metallo-β-lactamases NDM-1 and VIM-2." RSC Med Chem 14(11): 2277-2300.

29. Rafiei, V., et al. (2023). "Verticillium longisporum phospholipase VlsPLA(2) is a virulence factor that targets host nuclei and modulates plant immunity." Mol Plant Pathol 24(9): 1078-1092.

30. Raum, H. N., S. Z. Fisher and U. Weininger (2023). "Energetics and dynamics of the proton shuttle of carbonic anhydrase II." Cell Mol Life Sci 80(10): 286.

31. Sullivan, H. M., et al. (2023). Recombinant Protein Production Using the Baculovirus Expression Vector System (BEVS). Advanced Methods in Structural Biology. Â. Sousa and L. Passarinha. New York, NY, Springer US: 55-77.

32. Tamman, H., et al. (2023). "Structure of SpoT reveals evolutionary tuning of catalysis via conformational constraint." Nat Chem Biol 19(3): 334-345.

33. Torretta, A., et al. (2023). "PARP14 is a writer, reader, and eraser of mono-ADP-ribosylation." J Biol Chem 299(9): 105096.

34. Tükenmez, H., et al. (2023). "A Highly Substituted Ring-Fused 2-Pyridone Compound Targeting PrfA and the Efflux Regulator BrtA in Listeria monocytogenes." MBio 14(3).

35. Wallner, O., et al. (2023). "Optimization of N-Piperidinyl-Benzimidazolone Derivatives as Potent and Selective Inhibitors of 8-Oxo-Guanine DNA Glycosylase 1." ChemMedChem 18(1): e202200310.

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Publications 2022

1. S. Appelberg et al., A universal SARS-CoV DNA vaccine inducing highly cross-reactive neutralizing antibodies and T cells. EMBO Mol Med 14, e15821 (2022).

2. K. Asplund Hogelin et al., B-cell repopulation dynamics and drug pharmacokinetics impact SARSCoV-2 vaccine efficacy in anti-CD20-treated multiple sclerosis patients. Eur J Neurol 29, 3317-3328 (2022).

3. W. Bahnan et al., A human monoclonal antibody bivalently binding two different epitopes in streptococcal M protein mediates immune function. EMBO Mol Med 15, e16208 (2023).

4. E. Banijamali et al., RNA:RNA interaction in ternary complexes resolved by chemical
probing. RNA 29, 317-329 (2023).

5. M. Bartosovic, G. Castelo-Branco, Multimodal chromatin profiling using nanobody-based single-cell CUT&Tag. Nat Biotechnol 10.1038/s41587-022-01535-4 (2022).

6. M. Bartosovic, G. Castelo-Branco, Multimodal chromatin profiling using nanobody-based single-cell CUT&Tag. Nat Biotechnol 10.1038/s41587-022-01535-4 (2022).

7. L. Blixt et al., Covid-19 in patients with chronic lymphocytic leukemia: clinical outcome and B- and T-cell immunity during 13 months in consecutive patients. Leukemia 36, 476-481 (2022).

8. V. Bronnec, H. Eilers, A. C. Jahns, H. Omer, O. A. Alexeyev, Extracellular DNase BmdE Targeting. Front Cell Infect Microbiol 11, 809792 (2021).

9. S. Christensen, L. Groth, N. Leiva-Eriksson, M. Nyblom, L. Bulow, Oxidative Implications of Substituting a Conserved Cysteine Residue in Sugar Beet Phytoglobin BvPgb 1.2. Antioxidants (Basel) 11 (2022).

10. S. K. Das et al., MYC assembles and stimulates topoisomerases 1 and 2 in a "topoisome". Mol Cell 82, 140-158 e112 (2022).

11. B. J. Ding, H. L. Wang, M. A. Al-Saleh, C. Lofstedt, B. Antony, Bioproduction of (Z,E)-9,12-tetradecadienyl acetate (ZETA), the major pheromone component of Plodia, Ephestia, and Spodoptera species in yeast. Pest Manag Sci 78, 1048-1059 (2022).

12. C. Ebenwaldner et al., 14-3-3 Activated Bacterial Exotoxins AexT and ExoT Share Actin and the SH2 Domains of CRK Proteins as Targets for ADP-Ribosylation. Pathogens 11 (2022).

13. H. Feyrer, C. O. Gurdap, M. Marusic, J. Schlagnitweit, K. Petzold, Enzymatic incorporation of an isotope-labeled adenine into RNA for the study of conformational dynamics by NMR. PLoS One 17, e0264662 (2022).

14. D. K. Gahlot, S. N. Wai, D. L. Erickson, M. S. Francis, Cpx-signalling facilitates Hms-dependent biofilm formation by Yersinia pseudotuberculosis. NPJ Biofilms Microbiomes 8, 13 (2022).

15. C. Ge et al., Antibodies to cartilage oligomeric matrix protein are pathogenic in mice and may be clinically relevant in rheumatoid arthritis. Arthritis Rheumatol 10.1002/art.42072 (2022).

16. J. M. Gurung, A. A. A. Amer, S. Chen, A. Diepold, M. S. Francis, Type III secretion by Yersinia pseudotuberculosis is reliant upon an authentic N-terminal YscX secretor domain. Mol Microbiol 117, 886-906 (2022).

17. L. Hanke et al., A bispecific monomeric nanobody induces spike trimer dimers and neutralizes SARS-CoV-2 in vivo. Nat Commun 13, 155 (2022).

18. S. Havervall et al., Robust humoral and cellular immune responses and low risk for reinfection at least 8 months following asymptomatic to mild COVID-19. J Intern Med 291, 72-80 (2022).

19. Y. He et al., A subset of antibodies targeting citrullinated proteins confers protection from rheumatoid arthritis. Nat Commun 14, 691 (2023).

20. K. Healy et al., Salivary IgG to SARS-CoV-2 indicates seroconversion and correlates to serum neutralization in mRNA-vaccinated immunocompromised individuals. Med (N Y) 3, 137-153 e133 (2022).

21. A. S. Jemth et al., Nudix hydrolase 18 catalyzes the hydrolysis of active triphosphate metabolites of the antivirals Remdesivir, Ribavirin and Molnupiravir. J Biol Chem 10.1016/j.jbc.2022.102169, 102169 (2022).

22. X. Jia et al., V. cholerae MakA is a cholesterol-binding pore-forming toxin that induces noncanonical autophagy. J Cell Biol 221 (2022).

23. M. Jonsson et al., CaRA - A multi-purpose phage display library for selection of calcium-regulated affinity proteins. N Biotechnol 72, 159-167 (2022).

24. K. M. Kasmaei et al., Crystal structure of the feruloyl esterase from Lentilactobacillus buchneri reveals a novel homodimeric state. Front Microbiol 13, 1050160 (2022).

25. T. Kissel et al., Surface Ig variable domain glycosylation affects autoantigen binding and acts as threshold for human autoreactive B cell activation. Sci Adv 8, eabm1759 (2022).

26. T. O. Koller et al., Structural basis for HflXr-mediated antibiotic resistance in Listeria monocytogenes. Nucleic Acids Res 50, 11285-11300 (2022).

27. F. Kozielski et al., Identification of fragments binding to SARS-CoV-2 nsp10 reveals ligand-binding sites in conserved interfaces between nsp10 and nsp14/nsp16. RSC Chem Biol 3, 44-55 (2022).

28. T. Kurata et al., A hyperpromiscuous antitoxin protein domain for the neutralization of diverse toxin domains. Proc Natl Acad Sci U S A 119 (2022).

29. I. Lauren et al., Long-term SARS-CoV-2-specific and cross-reactive cellular immune responses correlate with humoral responses, disease severity, and symptomatology. Immun Inflamm Dis 10, e595 (2022).

30. T. Li et al., Pathogenic antibody response to glucose-6-phosphate isomerase targets a modified epitope uniquely exposed on joint cartilage. Ann Rheum Dis 10.1136/ard-2022-223633 (2023).

31. A. Luttens et al., Ultralarge Virtual Screening Identifies SARS-CoV-2 Main Protease Inhibitors with Broad-Spectrum Activity against Coronaviruses. J Am Chem Soc 144, 2905-2920 (2022).

32. J. Lyu, R. Shao, P. Y. Kwong Yung, S. J. Elsasser, Genome-wide mapping of G-quadruplex structures with CUT&Tag. Nucleic Acids Res 50, e13 (2022).

33. S. Malla et al., ZFP207 sustains pluripotency by coordinating OCT4 stability, alternative splicing and RNA export. EMBO Rep 23, e53191 (2022).

34. M. Michel et al., Small-molecule activation of OGG1 increases oxidative DNA damage repair by gaining a new function. Science 376, 1471-1476 (2022).

35. L. Moparthi et al., The human TRPA1 intrinsic cold and heat sensitivity involves separate channel structures beyond the N-ARD domain. Nat Commun 13, 6113 (2022).

36. S. Mravinacova et al., A cell-free high throughput assay for assessment of SARS-CoV-2 neutralizing antibodies. N Biotechnol 66, 46-52 (2022).

37. A. Nadeem et al., Protein-lipid interaction at low pH induces oligomerization of the MakA cytotoxin from Vibrio cholerae. Elife 11 (2022).

38. M. Orozco (2022) Reconstitution of Membrane-Bound Enzymes for Neutron Scattering Studies: A Case Study of Human Dihydroorotate Dehydrogenase. in Department of Biology (Lund University, Lund University (Media-Tryck)).

39. J. M. Orozco Rodriguez, E. Krupinska, H. Wacklin-Knecht, W. Knecht, Protein production, kinetic and biophysical characterization of three human dihydroorotate dehydrogenase mutants associated with Miller syndrome. Nucleosides Nucleotides Nucleic Acids 41, 1318-1336 (2022).

40. J. M. Orozco Rodriguez, H. Wacklin-Knecht, W. Knecht, Protein-lipid interactions of human dihydroorotate dehydrogenase and three mutants associated with Miller syndrome. Nucleosides Nucleotides Nucleic Acids 41, 1337-1358 (2022).

41. J. M. Orozco Rodriguez et al., New Insights into the Interaction of Class II Dihydroorotate Dehydrogenases with Ubiquinone in Lipid Bilayers as a Function of Lipid Composition. Int J Mol Sci 23 (2022).

42. K. Palica et al., Metallo-beta-Lactamase Inhibitor Phosphonamidate Monoesters. ACS Omega 7, 4550-4562 (2022).

43. F. Palm et al., Distinct Serotypes of Streptococcal M Proteins Mediate Fibrinogen-Dependent Platelet Activation and Proinflammatory Effects. Infect Immun 90, e0046221 (2022).

44. L. Persson Berg et al., Serum IgG levels to Epstein-Barr and measles viruses in patients with multiple sclerosis during natalizumab and interferon beta treatment. BMJ Neurol Open 4, e000271 (2022).

45. K. Pimkova et al., Quantitative analysis of redox proteome reveals oxidation-sensitive protein thiols acting in fundamental processes of developmental hematopoiesis. Redox Biol 53, 102343 (2022).

46. B. Prasad et al., A complementary chemical probe approach towards customized studies of Gquadruplex DNA structures in live cells. Chem Sci 13, 2347-2354 (2022).

47. D. Rehling et al., Structural and Biochemical Investigation of Class I Ribonucleotide Reductase from the Hyperthermophile Aquifex aeolicus. Biochemistry 61, 92-106 (2022).

48. M. Reihill et al., Synthesis of a B-Antigen Hexasaccharide, a B-Lewis b Heptasaccharide and Glycoconjugates Thereof to Investigate Binding Properties of Helicobacter pylori. Chemistry 10.1002/chem.202203672, e202203672 (2022).

49. E. Samuelsson et al., Sialic Acid and Fucose Residues on the SARS-CoV-2 Receptor-Binding Domain Modulate IgG Antibody Reactivity. ACS Infect Dis 8, 1883-1893 (2022).

50. H. Takada et al., Expression of Bacillus subtilis ABCF antibiotic resistance factor VmlR is regulated by RNA polymerase pausing, transcription attenuation, translation attenuation and (p)ppGpp. Nucleic Acids Res 50, 6174-6189 (2022).

51. H. Tamman et al., Structure of SpoT reveals evolutionary tuning of catalysis via conformational constraint. Nat Chem Biol 10.1038/s41589-022-01198-x (2022).

52. E. Toh et al., Bacterial protein MakA causes suppression of tumour cell proliferation via inhibition of PIP5K1α/Akt signalling. Cell Death Dis 13, 1024 (2022).

53. S. Vergani et al., A self-sustaining layer of early-life-origin B cells drives steady-state IgA responses in the adult gut. Immunity 55, 1829-1842 e1826 (2022).

54. A. Verma et al., Insights into the evolution of enzymatic specificity and catalysis: From Asgard archaea to human adenylate kinases. Sci Adv 8, eabm4089 (2022).

55. O. Wallner et al., Optimization of N-Piperidinyl-Benzimidazolone Derivatives as Potent and Selective Inhibitors of 8-Oxo-Guanine DNA Glycosylase 1. ChemMedChem 18, e202200310 (2023).

56. S. Wernersson, S. Birgersson, M. Akke, Cosolvent Dimethyl Sulfoxide Influences Protein-Ligand Binding Kinetics via Solvent Viscosity Effects: Revealing the Success Rate of Complex Formation Following Diffusive Protein-Ligand Encounter. Biochemistry 62, 44-52 (2023).

57. L. H. E. Wieske et al., NMR Backbone Assignment of VIM-2 and Identification of the Active Enantiomer of a Potential Inhibitor. ACS Medicinal Chemistry Letters 13, 257-261 (2022).

58. L. F. L. Wilson et al., The structure of EXTL3 helps to explain the different roles of bi-domain exostosins in heparan sulfate synthesis. Nat Commun 13, 3314 (2022).

59. A. J. L. Zheng et al., The nascent polypeptide-associated complex (NAC) controls translation initiation in cis by recruiting nucleolin to the encoding mRNA. Nucleic Acids Res 50, 10110-10122 (2022).

Last modified

4 July 2024