List of publications

Publications 2022

1. S. Appelberg et al., A universal SARS-CoV DNA vaccine inducing highly cross-reactive neutralizing antibodies and T cells. EMBO Mol Med 14, e15821 (2022).

2. K. Asplund Hogelin et al., B-cell repopulation dynamics and drug pharmacokinetics impact SARSCoV-2 vaccine efficacy in anti-CD20-treated multiple sclerosis patients. Eur J Neurol 29, 3317-3328 (2022).

3. W. Bahnan et al., A human monoclonal antibody bivalently binding two different epitopes in streptococcal M protein mediates immune function. EMBO Mol Med 15, e16208 (2023).

4. E. Banijamali et al., RNA:RNA interaction in ternary complexes resolved by chemical
probing. RNA 29, 317-329 (2023).

5. M. Bartosovic, G. Castelo-Branco, Multimodal chromatin profiling using nanobody-based single-cell CUT&Tag. Nat Biotechnol 10.1038/s41587-022-01535-4 (2022).

6. M. Bartosovic, G. Castelo-Branco, Multimodal chromatin profiling using nanobody-based single-cell CUT&Tag. Nat Biotechnol 10.1038/s41587-022-01535-4 (2022).

7. L. Blixt et al., Covid-19 in patients with chronic lymphocytic leukemia: clinical outcome and B- and T-cell immunity during 13 months in consecutive patients. Leukemia 36, 476-481 (2022).

8. V. Bronnec, H. Eilers, A. C. Jahns, H. Omer, O. A. Alexeyev, Extracellular DNase BmdE Targeting. Front Cell Infect Microbiol 11, 809792 (2021).

9. S. Christensen, L. Groth, N. Leiva-Eriksson, M. Nyblom, L. Bulow, Oxidative Implications of Substituting a Conserved Cysteine Residue in Sugar Beet Phytoglobin BvPgb 1.2. Antioxidants (Basel) 11 (2022).

10. S. K. Das et al., MYC assembles and stimulates topoisomerases 1 and 2 in a "topoisome". Mol Cell 82, 140-158 e112 (2022).

11. B. J. Ding, H. L. Wang, M. A. Al-Saleh, C. Lofstedt, B. Antony, Bioproduction of (Z,E)-9,12-tetradecadienyl acetate (ZETA), the major pheromone component of Plodia, Ephestia, and Spodoptera species in yeast. Pest Manag Sci 78, 1048-1059 (2022).

12. C. Ebenwaldner et al., 14-3-3 Activated Bacterial Exotoxins AexT and ExoT Share Actin and the SH2 Domains of CRK Proteins as Targets for ADP-Ribosylation. Pathogens 11 (2022).

13. H. Feyrer, C. O. Gurdap, M. Marusic, J. Schlagnitweit, K. Petzold, Enzymatic incorporation of an isotope-labeled adenine into RNA for the study of conformational dynamics by NMR. PLoS One 17, e0264662 (2022).

14. D. K. Gahlot, S. N. Wai, D. L. Erickson, M. S. Francis, Cpx-signalling facilitates Hms-dependent biofilm formation by Yersinia pseudotuberculosis. NPJ Biofilms Microbiomes 8, 13 (2022).

15. C. Ge et al., Antibodies to cartilage oligomeric matrix protein are pathogenic in mice and may be clinically relevant in rheumatoid arthritis. Arthritis Rheumatol 10.1002/art.42072 (2022).

16. J. M. Gurung, A. A. A. Amer, S. Chen, A. Diepold, M. S. Francis, Type III secretion by Yersinia pseudotuberculosis is reliant upon an authentic N-terminal YscX secretor domain. Mol Microbiol 117, 886-906 (2022).

17. L. Hanke et al., A bispecific monomeric nanobody induces spike trimer dimers and neutralizes SARS-CoV-2 in vivo. Nat Commun 13, 155 (2022).

18. S. Havervall et al., Robust humoral and cellular immune responses and low risk for reinfection at least 8 months following asymptomatic to mild COVID-19. J Intern Med 291, 72-80 (2022).

19. Y. He et al., A subset of antibodies targeting citrullinated proteins confers protection from rheumatoid arthritis. Nat Commun 14, 691 (2023).

20. K. Healy et al., Salivary IgG to SARS-CoV-2 indicates seroconversion and correlates to serum neutralization in mRNA-vaccinated immunocompromised individuals. Med (N Y) 3, 137-153 e133 (2022).

21. A. S. Jemth et al., Nudix hydrolase 18 catalyzes the hydrolysis of active triphosphate metabolites of the antivirals Remdesivir, Ribavirin and Molnupiravir. J Biol Chem 10.1016/j.jbc.2022.102169, 102169 (2022).

22. X. Jia et al., V. cholerae MakA is a cholesterol-binding pore-forming toxin that induces noncanonical autophagy. J Cell Biol 221 (2022).

23. M. Jonsson et al., CaRA - A multi-purpose phage display library for selection of calcium-regulated affinity proteins. N Biotechnol 72, 159-167 (2022).

24. K. M. Kasmaei et al., Crystal structure of the feruloyl esterase from Lentilactobacillus buchneri reveals a novel homodimeric state. Front Microbiol 13, 1050160 (2022).

25. T. Kissel et al., Surface Ig variable domain glycosylation affects autoantigen binding and acts as threshold for human autoreactive B cell activation. Sci Adv 8, eabm1759 (2022).

26. T. O. Koller et al., Structural basis for HflXr-mediated antibiotic resistance in Listeria monocytogenes. Nucleic Acids Res 50, 11285-11300 (2022).

27. F. Kozielski et al., Identification of fragments binding to SARS-CoV-2 nsp10 reveals ligand-binding sites in conserved interfaces between nsp10 and nsp14/nsp16. RSC Chem Biol 3, 44-55 (2022).

28. T. Kurata et al., A hyperpromiscuous antitoxin protein domain for the neutralization of diverse toxin domains. Proc Natl Acad Sci U S A 119 (2022).

29. I. Lauren et al., Long-term SARS-CoV-2-specific and cross-reactive cellular immune responses correlate with humoral responses, disease severity, and symptomatology. Immun Inflamm Dis 10, e595 (2022).

30. T. Li et al., Pathogenic antibody response to glucose-6-phosphate isomerase targets a modified epitope uniquely exposed on joint cartilage. Ann Rheum Dis 10.1136/ard-2022-223633 (2023).

31. A. Luttens et al., Ultralarge Virtual Screening Identifies SARS-CoV-2 Main Protease Inhibitors with Broad-Spectrum Activity against Coronaviruses. J Am Chem Soc 144, 2905-2920 (2022).

32. J. Lyu, R. Shao, P. Y. Kwong Yung, S. J. Elsasser, Genome-wide mapping of G-quadruplex structures with CUT&Tag. Nucleic Acids Res 50, e13 (2022).

33. S. Malla et al., ZFP207 sustains pluripotency by coordinating OCT4 stability, alternative splicing and RNA export. EMBO Rep 23, e53191 (2022).

34. M. Michel et al., Small-molecule activation of OGG1 increases oxidative DNA damage repair by gaining a new function. Science 376, 1471-1476 (2022).

35. L. Moparthi et al., The human TRPA1 intrinsic cold and heat sensitivity involves separate channel structures beyond the N-ARD domain. Nat Commun 13, 6113 (2022).

36. S. Mravinacova et al., A cell-free high throughput assay for assessment of SARS-CoV-2 neutralizing antibodies. N Biotechnol 66, 46-52 (2022).

37. A. Nadeem et al., Protein-lipid interaction at low pH induces oligomerization of the MakA cytotoxin from Vibrio cholerae. Elife 11 (2022).

38. M. Orozco (2022) Reconstitution of Membrane-Bound Enzymes for Neutron Scattering Studies: A Case Study of Human Dihydroorotate Dehydrogenase. in Department of Biology (Lund University, Lund University (Media-Tryck)).

39. J. M. Orozco Rodriguez, E. Krupinska, H. Wacklin-Knecht, W. Knecht, Protein production, kinetic and biophysical characterization of three human dihydroorotate dehydrogenase mutants associated with Miller syndrome. Nucleosides Nucleotides Nucleic Acids 41, 1318-1336 (2022).

40. J. M. Orozco Rodriguez, H. Wacklin-Knecht, W. Knecht, Protein-lipid interactions of human dihydroorotate dehydrogenase and three mutants associated with Miller syndrome. Nucleosides Nucleotides Nucleic Acids 41, 1337-1358 (2022).

41. J. M. Orozco Rodriguez et al., New Insights into the Interaction of Class II Dihydroorotate Dehydrogenases with Ubiquinone in Lipid Bilayers as a Function of Lipid Composition. Int J Mol Sci 23 (2022).

42. K. Palica et al., Metallo-beta-Lactamase Inhibitor Phosphonamidate Monoesters. ACS Omega 7, 4550-4562 (2022).

43. F. Palm et al., Distinct Serotypes of Streptococcal M Proteins Mediate Fibrinogen-Dependent Platelet Activation and Proinflammatory Effects. Infect Immun 90, e0046221 (2022).

44. L. Persson Berg et al., Serum IgG levels to Epstein-Barr and measles viruses in patients with multiple sclerosis during natalizumab and interferon beta treatment. BMJ Neurol Open 4, e000271 (2022).

45. K. Pimkova et al., Quantitative analysis of redox proteome reveals oxidation-sensitive protein thiols acting in fundamental processes of developmental hematopoiesis. Redox Biol 53, 102343 (2022).

46. B. Prasad et al., A complementary chemical probe approach towards customized studies of Gquadruplex DNA structures in live cells. Chem Sci 13, 2347-2354 (2022).

47. D. Rehling et al., Structural and Biochemical Investigation of Class I Ribonucleotide Reductase from the Hyperthermophile Aquifex aeolicus. Biochemistry 61, 92-106 (2022).

48. M. Reihill et al., Synthesis of a B-Antigen Hexasaccharide, a B-Lewis b Heptasaccharide and Glycoconjugates Thereof to Investigate Binding Properties of Helicobacter pylori. Chemistry 10.1002/chem.202203672, e202203672 (2022).

49. E. Samuelsson et al., Sialic Acid and Fucose Residues on the SARS-CoV-2 Receptor-Binding Domain Modulate IgG Antibody Reactivity. ACS Infect Dis 8, 1883-1893 (2022).

50. H. Takada et al., Expression of Bacillus subtilis ABCF antibiotic resistance factor VmlR is regulated by RNA polymerase pausing, transcription attenuation, translation attenuation and (p)ppGpp. Nucleic Acids Res 50, 6174-6189 (2022).

51. H. Tamman et al., Structure of SpoT reveals evolutionary tuning of catalysis via conformational constraint. Nat Chem Biol 10.1038/s41589-022-01198-x (2022).

52. E. Toh et al., Bacterial protein MakA causes suppression of tumour cell proliferation via inhibition of PIP5K1α/Akt signalling. Cell Death Dis 13, 1024 (2022).

53. S. Vergani et al., A self-sustaining layer of early-life-origin B cells drives steady-state IgA responses in the adult gut. Immunity 55, 1829-1842 e1826 (2022).

54. A. Verma et al., Insights into the evolution of enzymatic specificity and catalysis: From Asgard archaea to human adenylate kinases. Sci Adv 8, eabm4089 (2022).

55. O. Wallner et al., Optimization of N-Piperidinyl-Benzimidazolone Derivatives as Potent and Selective Inhibitors of 8-Oxo-Guanine DNA Glycosylase 1. ChemMedChem 18, e202200310 (2023).

56. S. Wernersson, S. Birgersson, M. Akke, Cosolvent Dimethyl Sulfoxide Influences Protein-Ligand Binding Kinetics via Solvent Viscosity Effects: Revealing the Success Rate of Complex Formation Following Diffusive Protein-Ligand Encounter. Biochemistry 62, 44-52 (2023).

57. L. H. E. Wieske et al., NMR Backbone Assignment of VIM-2 and Identification of the Active Enantiomer of a Potential Inhibitor. ACS Medicinal Chemistry Letters 13, 257-261 (2022).

58. L. F. L. Wilson et al., The structure of EXTL3 helps to explain the different roles of bi-domain exostosins in heparan sulfate synthesis. Nat Commun 13, 3314 (2022).

59. A. J. L. Zheng et al., The nascent polypeptide-associated complex (NAC) controls translation initiation in cis by recruiting nucleolin to the encoding mRNA. Nucleic Acids Res 50, 10110-10122 (2022).